Transcatheter Aortic Valve Replacement


Transcatheter Aortic Valve Replacement (TAVR)

What is transcatheter aortic valve replacement?

  • The aortic valve guards flow of blood from the heart to the rest of the body. The major blood vessel that carries blood to the various organs of the body is the aorta and hence this valve is named aortic valve.
  • Aortic stenosis is a condition where the aortic valve narrows due to various causes. Most commonly ageing consequent degeneration of aortic valve causes the narrowing thus restricting blood flow to other organs.
  • Transcatheter Aortic Valve Replacement (TAVR or TAVI) is a procedure where the damaged valve is replaced by an artificial valve.
  • TAVR is a minimally invasive procedure and does not require splitting open of chest or general anaesthesia.
  • Through an incision, in the groin, an aortic valve mounted on a catheter will be introduced into the heart.
  • Then, an artificial valve is directed into the aortic valve, where it can be expanded and further takes over the function of a diseased valve resulting in improved blood flow.

Aortic Stenosis

Why TAVR became a revolutionary popular procedure?

  • Aortic valve degenerates with ageing due to wear and tear. This happens usually beyond the age of 65 years. Many at that age have associated issues like previous heart surgery, kidney dysfunction, blocks in blood vessels supplying heart and brain, age-related frailty, lung problems etc. These issues make them a high risk for open-heart surgery.
  • Initially, TAVR was indicated for high-risk patients but for the past 5 years is being used in intermediate-risk and selected low-risk cases also.

Who are eligible to undergo TAVR procedure?

  • High risk for open-heart surgery
  • History of kidney or lung diseases and cannot undergo invasive procedures/surgery
  • Having previous valve replacement surgery that gets narrowed again.

Who are not eligible to undergo TAVR procedure?

  • Previous mechanical valve surgery at the aortic valve location.

What are the risks of the TAVR procedure?

Generally, the TAVR procedure is safe and effective. However, some problems may occur in 1-3% of cases based on an individual’s characteristics which include:

  • Bleeding due to damage of blood vessels
  • Brain stroke
  • Infection
  • Heart attack
  • Kidney failure
  • Failure of the new artificial valve

aortic valve surgery

What are the potential complications of the TAVR procedure?

  • Paravalvular regurgitation
  • Pacemaker implantation
  • Valve thrombosis
  • Bleeding
  • Infective endocarditis
  • Death

These can potentially affect 0.5-7% of patients.

What are diagnostic tests to undergo before the TAVR procedure?

  • Electrocardiogram
  • Echocardiogram
  • Transesophageal echocardiogram
  • Carotid Ultrasound
  • CT aortogram

What happens during TAVR procedure?

  • Small incisions are made in the groin for catheter insertion. Ongoing X-ray imaging will guide the catheter towards the aortic valve and the balloon at the end of the catheter may be inflated to open the aortic valve.
  • Then an artificial aortic valve will be directed through the catheter and placed over the diseased valve and deployed.
  • Echocardiography will be done to check for the functioning of the new aortic valve.

 What happens after the TAVR procedure?

  • Vitals such as Blood pressure, heart rate, temperature, respiration rate, blood oxygen level will be monitored, the patent is rested in the ICU for 24 hours.
  • Patient hospital stay will be 2 to 4 days.
  • If the catheter insertion is at the groin area, you may ask for not bend or cross your legs
  • Infections and bleeding manifestations are checked at the insertion site
  • You will be instructed to keep hydrated that will help you in washing off the contrast dye
  • Blood tests, Chest X-ray, Electrocardiogram(ECG), Echocardiogram will be done

 How long does my TAVR procedure last?

  • TAVR is a durable procedure and lasts for 10 to 20 years in the absence of complications.
  • Compared to surgical replacement of the aortic valve, TAVR provides a larger valve area and hence chances for re-narrowing are less.
tavr
tavr 2
tavr 1

How does TAVR compare with Aortic valve replacement surgery?

 

TAVR

Aortic valve replacement surgery
The damaged aortic valve is replaced with an artificial valve without open-heart surgery by accessing the heart through the groin The damaged aortic valve is replaced with an artificial valve by open-heart surgery using a heart-lung machine
Advantages: Advantages:
The modern approach to valve replacement Time tested approach to valve replacement
Valve sizing is superior in TAVR as multiple imaging modalities are utilized. Can be performed in patients with infection of the heart
Larger valve area in TAVR compared to surgery AVR leading to long-lasting valve durability. Those with associated dilation of the aorta
Useful in patients with multiple co-existing illnesses like kidney dysfunction, narrowing of blood vessels supplying brain and heart, elderly age, lung problem, previous bypass or valve replacement surgery, frailty etc. Low-risk cases surgery may be preferred
Minimal pain
Only small incision
Shorter hospital stay
The chest is not cut open
Fast Recovery rate
Less anxiety and mental illness
The procedure can be repeated if the valve gets degenerated after 10-15 years.
Limitations: Limitations:
Not possible when there is an infection of the heart Chest cut open
Not suitable when there ascending aortic aneurysm Delayed recovery
Expensive procedure If mechanical valve used, subsequent TAVR is not possible
Longer hospital stay
Not suitable for very elderly, those with kidney dysfunction before bypass surgery and blocks in blood vessels supplying the brain

What is the uniqueness of treatment of TAVR by Dr C Raghu?

  • Availability of multimodality imaging leading to accurate diagnosis of the problem and associated co-morbidities.
  • One of the earliest cardiologists in India to have performed TAVR.
  • The first operator in South India to have performed TAVR in a patient with a previous mitral valve replacement.
  • Excellent pre-procedure planning leading to a highly successful result.

Keywords:

  • Open heart surgery
  • Mechanical valve
  • Pacemaker
  • Valve Thrombosis
  • Infective endocarditis
  • Echocardiograms
  • Carotid ultrasound
  • Ct Aortogram
  • Artificial aortic valve
  • TAVR procedure
  • Fast recovery rate
  • Small incision
  • Cardiologist
  • Mitral valve replacement


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Copyright © 2019, Dr C Raghu. All rights reserved.
Designed & Developed by R R Deepak Kambhampati.



Copyright © 2019, Dr C Raghu. All rights reserved.
Designed & Developed by R R Deepak Kambhampati.